What is Centella Extract 4:1?
Centella Extract 4:1 is a standardized herbal extract (4:1) obtained from the Gotu kola plant. It is used as a raw material in the production of dietary supplements.
Product Features
- Part used: Aerial Parts
- Standardization: 4:1
- Solubility: Water-soluble
| Analysis | Value |
|---|---|
| Moisture | ≤5.0 % |
| Total Heavy Metals | ≤10 ppm |
| E.Coli | Negative in 10 g |
| Salmonella | Negative in 25 g |
What is Centella Extract 4:1 Used For? What is its Purpose?
What is Centella Extract 4:1 used for? Gotu Kola (Centella asiatica) is a standardized herbal raw material used in dietary supplements for skin/wound healing, venous circulation, and mental/relaxation support due to its content of triterpenoid saponins: asiaticoside, madecassoside; asiatic acid, madecassic acid. With its standardized 4:1 content, it provides a consistent source of ingredients in formulations such as capsules, tablets, standardized extracts (TECA), powders, topical creams/ointments, and teas.
Benefits and Main Uses of Centella Extract 4:1
- Venous circulation: Used to reduce symptoms in chronic venous insufficiency (heavy, tired legs, edema, pain) with titrated extract (TECA).
- Wound and skin healing: Used traditionally and topically to accelerate the healing of minor wounds and burns and to improve the appearance of scars/keloids.
- Skin integrity and collagen: Preferred in supplements for skin firmness and tissue repair because triterpenoids support collagen synthesis.
- Relaxation and cognitive support: Small-scale human studies have shown an anxiolytic effect; traditionally used for memory support (limited evidence).
Mechanism of Action and Active Components
Triterpenoids such as asiaticoside and madecassoside strengthen the venous wall and accelerate tissue repair by supporting collagen synthesis and micro-circulation; they also exhibit antioxidant and anti-inflammatory effects.
Forms of Use (Tablet, Capsule, Powder)
The powder form can be used in tablet, capsule, powder mixture/sachet, and (being water-soluble) liquid/syrup formulations.
Positive List of Plants Check
Gotu kola is among the permitted (positive) plants under the Turkish Food Codex regulations for dietary supplements. The permitted/used part is: Aerial Parts.
Usage Rate in Dietary Supplements
According to the Restricted Substances List for Dietary Supplements, a daily usage limit of 18 mg/day applies to this component/extract. Label warning: The warning "Should not be used during pregnancy" must be displayed.
Storage, Shelf Life, and Re-test
Store in a cool, dry place protected from light. The recommended re-test period is generally 3 years; it varies by manufacturer. The CoA document of the relevant batch shall be taken as the basis for the exact date.
Technical Documents and Supply — Asuka Kimya
You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for Centella Extract 4:1.
References
The usage information on this page is compiled from official herbal monographs and scientific literature (e.g., EMA/HMPC, NIH/NCCIH, Cochrane, EFSA). The product is a dietary supplement raw material and is not intended for the diagnosis or treatment of disease.