What is Bitter Melon Extract 4:1?

Bitter Melon Extract 4:1 is a standardized herbal extract (4:1) obtained from the bitter melon plant. It is used as a raw material in dietary supplement production.

Product Properties

  • Part used: Fruit
  • Standardization: 4:1
  • Solubility: Water-soluble
AnalysisValue
Moisture ≤5.0 %
Total Heavy Metals ≤10 ppm
E.ColiNegative in 10 g
SalmonellaNegative in 25 g

What is Bitter Melon Extract 4:1 Used For? What is its Purpose?

What is Bitter Melon Extract 4:1 used for? Bitter melon is a standardized herbal raw material traditionally used in dietary supplements for supporting blood sugar / glucose metabolism balance, due to its content of charantin, polypeptide-p, and vicine (bitter components). With its standardized 4:1 content, it provides a consistent ingredient source in formulations such as fruit extract capsules, powders, teas, and standardized extracts.

Benefits and Main Uses of Bitter Melon Extract 4:1

  • Blood sugar support: Known in traditional medicine for its hypoglycemic effects; some 12-week studies have reported reductions in fasting blood sugar and glucose tolerance.
  • Metabolic balance: While some individual clinical studies have shown positive effects on glycemic control, evidence from meta-analyses is limited and inconsistent.
  • Traditional use: Traditionally used to support diabetes and digestive complaints.
  • Antioxidant content: The fruit is traditionally consumed for general health support due to various bioactive compounds.

Mechanism of Action and Active Components

It is suggested that components such as charantin and insulin-like polypeptide-p exhibit insulin-like effects and support glucose uptake; however, clinical evidence is limited due to a lack of standardization.

Forms of Use (Tablet, Capsule, Powder)

The powder form can be used in tablet, capsule, powder mix/sachet, and (being water-soluble) liquid/syrup formulations.

Positive Plant List Check

Bitter melon is included among the plants permitted for use (positive list) under the Turkish Food Codex regulations for dietary supplements. The permitted/used part: Fruit.

Usage Rate in Dietary Supplements

According to the List of Restricted Substances in Dietary Supplements, a daily usage limit of 50mg/day applies to this component/extract. Label warning: “Allergic reactions may occur. It may move gallstones.”

Storage, Shelf Life, and Re-test

Store in a cool, dry place protected from light. The recommended re-test period is generally 3 years, but it may vary by manufacturer. The CoA (Certificate of Analysis) for the relevant batch should be consulted for the exact date.

Technical Documents and Supply — Asuka Kimya

You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for Bitter Melon Extract 4:1.

References

  1. ncbi.nlm.nih.gov
  2. pubmed.ncbi.nlm.nih.gov

The usage information on this page is compiled from official herbal monographs and scientific literature (e.g., EMA/HMPC, NIH/NCCIH, Cochrane, EFSA). The product is a dietary supplement raw material and is not intended for the diagnosis or treatment of disease.