What is Dicalcium Phosphate Dihydrate (Di Calcium Phosphate - Mineral)?
Dicalcium phosphate dihydrate is a white, odorless, crystalline calcium-phosphorus salt with low solubility in water (E341(ii)). It is used in supplements as both a source of calcium/phosphorus and as a tablet filler/compression agent; it also serves as a mild abrasive in toothpaste. Calcium and phosphorus are fundamental components of skeletal mineralization.
- Molecular formula: CaHPO₄ ⋅ 2H₂O
- CAS number: 7789-77-7
- Form: Powder / Inorganic Calcium Phosphate Salt
- Quality: Food / Pharmaceutical Grade
- Dicalcium phosphate dihydrate (CaHPO4·2H2O, CAS 7789-77-7) contains ~23% calcium and ~18% phosphorus by weight; it is a source of both calcium and phosphorus. Due to its low solubility in water, it is also preferred as a neutral filler in tablets.
What is Di Calcium Phosphate - Mineral Used For? Why is it Used?
Dicalcium phosphate dihydrate is an efficient mineral source in bone/tooth health formulations because it provides both calcium and phosphorus in a single compound. With excellent compression/flow properties, it serves a dual function as a filler/excipient in tablets and provides leavening, buffering, and fortification in the food industry as the E341(ii) food additive.
Main areas of use: Dietary Supplements.
Usage in Dietary Supplements
- Source of calcium and phosphorus: It is an authorized mineral source providing both calcium and phosphorus in a single compound (dosed based on Ca NRV 800 mg, P NRV 700 mg).
- Tablet filler / excipient: Due to its low solubility, good flow, and compressibility, it is used as a filler and direct compression agent in tablets; it serves both as a mineral and a technological excipient.
- Bone health formulations: The calcium+phosphorus combination provides the building blocks of hydroxyapatite, so it is used in bone support supplements (usually with Vitamin D).
- Abrasive in toothpaste: It is used as a mild abrasive in oral care products to remove plaque/stains; it also serves as a source of calcium/phosphate.
Usage in the Food Industry
- E341(ii) food additive: In the EU, it belongs to the class of calcium phosphates under the additive number E341(ii); it is used as a component of baking powder, acidity regulator, stabilizer, anti-caking agent, and water-retaining salt.
- Leavening and mineral fortification: It is used as the acid component of baking powder and as a source of calcium/phosphorus fortification in flour, dough products, and crispbreads.
- Anti-caking agent: It is used as an anti-caking agent to maintain free flow in powdered foods.
Effects on Health
Calcium and Phosphorus are mineral components that play various essential roles in the body. The main functions authorized/evaluated by the European Food Safety Authority (EFSA):
- Bones and teeth: Calcium and phosphorus contribute to the maintenance of normal bones and teeth; together they form the hydroxyapatite matrix (EFSA).
- Energy metabolism: Phosphorus contributes to normal energy metabolism via ATP and phosphate esters (EFSA).
- Muscle function: Calcium contributes to normal muscle function and neurotransmission (EFSA).
- Cell membranes: Phosphorus contributes to the normal function of cell membranes (phospholipids) (EFSA).
- Blood coagulation and digestive enzymes: Calcium contributes to normal blood coagulation and the normal function of digestive enzymes (EFSA).
- Calcium-phosphorus balance: Bone health depends on the balanced intake of calcium and phosphorus; both are regulated by PTH, Vitamin D, and FGF23.
Usage Limits in Dietary Supplements
- Nutrient Reference Value (NRV): Calcium NRV 800 mg; Phosphorus NRV 700 mg (1169/2011).
- Tolerable Upper Intake Level (EFSA): Calcium UL 2500 mg/day (EFSA). EFSA has NOT SET a numerical UL for phosphorus; it is tolerated at levels of ~3000 mg/day.
- Turkish legislation (TETGK): Dicalcium phosphate is an authorized calcium/phosphorus source in the TR Regulation and is authorized as E341 in the Food Additives Regulation. Current supplements should be consulted for exact numerical supplement limits.
In cases of renal failure, high phosphorus intake should be limited; the calcium-phosphorus ratio is important for bone health.
Technical Specifications
| Parameter | Value |
|---|---|
| Purity | 98–100% |
| Appearance | White Crystalline Powder |
| Moisture | ≤5.0 % |
| Solubility | Insoluble in Water |
Scientific Studies
The following independent research studies relate to the bioavailability, usage, and effects of this mineral (evidence levels are specified):
- PubMed 25905252 — Review examining calcium and phosphorus homeostasis.
- PubMed 36545737 — Review examining phosphorus homeostasis and disorders of phosphorus metabolism.
- PubMed 21985972 — Review examining regulators of calcium and phosphorus homeostasis.
Technical Documents and Supply — Asuka Kimya
You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for Dicalcium Phosphate Dihydrate.
References
- doi.org
- eur-lex.europa.eu
- efsa.europa.eu
- ods.od.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
The usage and health information on this page has been compiled from official legislation/institution sources (EFSA, NIH ODS, Turkish Food Codex, EUR-Lex) and independent scientific publications (PubMed). The product is a food supplement/food raw material; it does not claim to diagnose or treat diseases.