What is Grape Seed Extract 25:1?
Grape Seed Extract 25:1 is a standardized herbal extract (25:1) obtained from the Grape seed plant. It is used as a raw material in dietary supplement production.
Product Properties
- Part used: Seed
- Standardization: 25:1
- Solubility: Water-soluble
| Analysis | Value |
|---|---|
| Moisture | ≤5.0 % |
| Total Heavy Metals | ≤10 ppm |
| E. Coli | Negative in 10 g |
| Salmonella | Negative in 25 g |
What is Grape Seed Extract 25:1 Used For? What is its Purpose?
What is Grape Seed Extract 25:1 used for? Grape Seed is a standardized herbal raw material used in dietary supplements for strong antioxidant support and vascular/circulatory health due to its content of Oligomeric Proanthocyanidins (OPC) and polyphenols. With its standardized 25:1 content, it provides a consistent ingredient source in formulations such as capsules, tablets, and powdered extracts (usually standardized to 95% proanthocyanidins).
Grape Seed Extract 25:1 Benefits and Main Areas of Use
- Antioxidant Protection: The oligomeric proanthocyanidins it contains are powerful antioxidants; they help protect cells from oxidative damage caused by free radicals.
- Vascular and Leg Circulation: Improvement has been shown in placebo-controlled studies for symptoms of chronic venous insufficiency (heaviness and swelling in the legs); it is used to support venous health and microcirculation.
- Edema and Capillary Resistance: It is used to support capillary permeability and durability, and to reduce edema after injury or surgery.
- Cardiovascular Health: It has been studied regarding cardiovascular risk factors; evidence for definitive conclusions is currently limited (limited evidence).
Mechanism of Action and Active Components
OPCs act as powerful antioxidants that neutralize free radicals and support the resistance of capillary and venous walls by preserving the collagen/elastin structure.
Forms of Use (Tablet, Capsule, Powder)
The powder form can be used in tablet, capsule, powder mix/sachet, and (being water-soluble) liquid/syrup formulations.
Positive List of Plants Check
Grape seed is included among the plants permitted for use (positive list) under Turkish Food Codex dietary supplement legislation. The permitted/used part: Seed.
Usage Rate in Dietary Supplements
According to the Restricted Substances List for Dietary Supplements, a daily usage limit of 500mg/day applies to this component/extract.
Storage, Shelf Life, and Re-test
Store in a cool, dry place protected from light. The recommended re-test period is generally 3 years; it varies by manufacturer. The CoA document of the relevant batch shall be taken as the basis for the exact date.
Technical Documents and Supply — Asuka Kimya
You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for Grape Seed Extract 25:1.
References
The usage information on this page is compiled from official herbal monographs and scientific literature (e.g., EMA/HMPC, NIH/NCCIH, Cochrane, EFSA). The product is a dietary supplement raw material; it does not claim to diagnose or treat diseases.

