What is Magnesium Malate Anhydrous Granular (Magnesium Malate Anhydrous Granular · Dietary Supplement)?
Magnesium malate is an organic salt formed by magnesium and malic acid (apple acid) (CAS 869-06-7). As an organic salt, it generally has better solubility and absorption compared to inorganic oxides/hydroxides. Malic acid is a natural dicarboxylic acid involved in cellular energy production (Krebs cycle).
- Molecular formula: C₄H₄MgO₅
- CAS number: 869-06-7
- Form: Granular
- Quality: Food / Pharmaceutical Grade
- Anhydrous magnesium malate contains approximately 15–16% elemental Mg; mixed di-magnesium malate forms contain ~12–15% (EFSA).
What is Magnesium Malate Anhydrous Granular · Dietary Supplement Used For? Why is it Used?
As an organic salt, magnesium malate offers good solubility and good tolerability (low laxative effect); the malic acid component is associated with energy metabolism. It is suitable for formulations seeking to administer high doses of general magnesium supplementation without causing stomach upset.
Main areas of use: Dietary Supplements, Energy Production, Muscle Function, Digestive System, Tablet Manufacturing, Granule Mixtures.
Usage in Dietary Supplements
- Organic salt, good tolerance: Chelated/organic magnesium forms are generally better absorbed and better tolerated in the GI tract than magnesium oxide; malate is among the forms with low laxative effects.
- Malic acid and energy context: Both magnesium and malic acid play a role in ATP synthesis; this pair is used together in supplements associated with energy metabolism (specific clinical evidence is limited).
- Fibromyalgia research history: The magnesium + malic acid combination has been researched for fibromyalgia in the past; the level of evidence is weak/limited.
- Divided daily dose: Like other magnesium salts, elemental magnesium is taken in divided doses for tolerance; the label must declare elemental Mg.
Usage in the Food Industry
- Permitted magnesium source: EU (EC) 1170/2009 lists magnesium malate among permitted magnesium sources for supplements and fortified foods.
- Di-magnesium malate / EFSA: EFSA has evaluated di-magnesium malate as a magnesium source, stating that magnesium is bioavailable.
- Taste/acidity profile: Due to the slightly sour profile of malic acid, it may be preferred in some functional powder/beverage formulations for flavor and solubility (malic acid E296).
Effects on Health
Magnesium is a mineral that plays a role in many fundamental functions in the body. The main functions authorized/evaluated by the European Food Safety Authority (EFSA):
- Normal muscle function: Magnesium contributes to normal muscle function (EFSA).
- Reduction of fatigue: Magnesium contributes to the reduction of fatigue (EFSA ID 244).
- Energy metabolism: Magnesium contributes to normal energy metabolism; it is a cofactor in ATP production (EFSA).
- Nervous system: Magnesium contributes to the normal functioning of the nervous system and psychological function (EFSA).
- Protein synthesis and cell division: Magnesium contributes to normal protein synthesis and cell division (EFSA).
- Bones and teeth: Magnesium contributes to the maintenance of bones/teeth and electrolyte balance (EFSA).
Usage Limits in Dietary Supplements
- Nutrient Reference Value (NRV): Mg NRV 375 mg (1169/2011).
- Upper Level of Intake (EFSA): EFSA/SCF: UL for added magnesium is 250 mg/day.
- Turkish legislation (TSEF): The TR list of permitted magnesium compounds is compatible with EU 1170/2009; malate is permitted. A specific numerical upper limit for malate could not be verified.
In mixed salt forms, EFSA reports magnesium content at ~12–15%; the label is based on elemental Mg.
Technical Specifications
| Parameter | Value |
|---|---|
| Purity (Mg) | ≥14.7 |
| Appearance | White Irregular Granules |
| Moisture | ≤5.0 % |
| Solubility | Soluble in Water |
Scientific Studies
The following independent studies relate to the bioavailability, usage, and effects of this mineral (levels of evidence are specified):
- PubMed 8587088 — Randomized double-blind placebo-controlled crossover pilot study investigating the effect of malic acid + magnesium in fibromyalgia.
- PubMed 35253448 — Randomized controlled study comparing the effects of different magnesium salts on arterial stiffness.
- PubMed 29679349 — Human study comparing the hourly bioavailability of different magnesium compounds.
Technical Documents and Supply — Asuka Kimya
You can contact Asuka Kimya for SDS, TDS, CoA and supply conditions for Magnesium Malate Anhydrous Granular.
References
- ods.od.nih.gov
- efsa.onlinelibrary.wiley.com
- eur-lex.europa.eu
- resmigazete.gov.tr
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
- pubmed.ncbi.nlm.nih.gov
The usage and health information on this page has been compiled from official legislation/institution sources (EFSA, NIH ODS, Turkish Food Codex, EUR-Lex) and independent scientific publications (PubMed). The product is a food supplement/food raw material and is not intended for the diagnosis or treatment of disease.