What is Polygonum Cuspidatum Extract 25:1?
Polygonum Cuspidatum Extract 25:1 is a standardized herbal extract (25:1) obtained from the Polygonum cuspidatum plant. It is used as a raw material in dietary supplement production.
Product Properties
- Part used: Root
- Standardization: 25:1
- Solubility: Water-soluble
| Analysis | Value |
|---|---|
| Moisture | ≤5.0 % |
| Total Heavy Metals | ≤10 ppm |
| E.Coli | Negative in 10 g |
| Salmonella | Negative in 25 g |
What is Polygonum Cuspidatum Extract 25:1 Used For? What is its Purpose?
What is Polygonum Cuspidatum Extract 25:1 used for? Japanese Knotweed (Resveratrol), with its Trans-resveratrol (and emodin) content, is a standardized herbal raw material used in dietary supplements for antioxidant, cardiovascular, and healthy aging support (resveratrol source) purposes. With its standardized 25:1 content, the standardized root extract (%50-98 trans-resveratrol) provides a consistent ingredient source in formulations such as capsules and powders.
Benefits and Main Uses of Polygonum Cuspidatum Extract 25:1
- Antioxidant Protection: Resveratrol, a powerful polyphenol, is being researched for its potential to reduce oxidative stress and free radical damage.
- Cardiovascular Health: A systematic review reported that resveratrol may be effective in lowering blood pressure, oxidative stress, and inflammation (limited evidence).
- Anti-inflammatory Support: P. cuspidatum extract (containing resveratrol) has been evaluated in clinical studies for anti-inflammatory effects (limited evidence).
- Traditional Use: The root has been used in Traditional Chinese Medicine for a long time; extensive human studies for many uses are currently limited (traditionally).
Mechanism of Action and Active Components
Trans-resveratrol is an antioxidant and anti-inflammatory polyphenol that clears free radicals; its effects on endothelial function and cellular signaling pathways are being investigated.
Forms of Use (Tablet, Capsule, Powder)
The powder form can be used in tablet, capsule, powder mix/sachet, and (being water-soluble) liquid/syrup formulations.
Positive Plant List Check
Polygonum cuspidatum is included among the permitted (positive) plants under the Turkish Food Codex dietary supplement legislation. The permitted/used part: Root.
Usage Rate in Dietary Supplements
According to the Restricted Substances List for Dietary Supplements, a daily usage limit of 500mg/day applies to this component/extract.
Storage, Shelf Life, and Re-test
Store in a cool, dry, and protected from light environment. The recommended re-test period is generally 3 years; it may vary by manufacturer. The CoA document of the relevant batch shall be taken as the basis for the exact date.
Technical Documents and Supply — Asuka Kimya
You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for Polygonum Cuspidatum Extract 25:1.
References
The usage information on this page is compiled from official herbal monographs and scientific literature (e.g., EMA/HMPC, NIH/NCCIH, Cochrane, EFSA). The product is a dietary supplement raw material and is not intended for the diagnosis or treatment of disease.

