What is Polygonum Cuspidatum Extract 25:1?

Polygonum Cuspidatum Extract 25:1 is a standardized herbal extract (25:1) obtained from the Polygonum cuspidatum plant. It is used as a raw material in dietary supplement production.

Product Properties

  • Part used: Root
  • Standardization: 25:1
  • Solubility: Water-soluble
AnalysisValue
Moisture ≤5.0 %
Total Heavy Metals ≤10 ppm
E.ColiNegative in 10 g
SalmonellaNegative in 25 g

What is Polygonum Cuspidatum Extract 25:1 Used For? What is its Purpose?

What is Polygonum Cuspidatum Extract 25:1 used for? Japanese Knotweed (Resveratrol), with its Trans-resveratrol (and emodin) content, is a standardized herbal raw material used in dietary supplements for antioxidant, cardiovascular, and healthy aging support (resveratrol source) purposes. With its standardized 25:1 content, the standardized root extract (%50-98 trans-resveratrol) provides a consistent ingredient source in formulations such as capsules and powders.

Benefits and Main Uses of Polygonum Cuspidatum Extract 25:1

  • Antioxidant Protection: Resveratrol, a powerful polyphenol, is being researched for its potential to reduce oxidative stress and free radical damage.
  • Cardiovascular Health: A systematic review reported that resveratrol may be effective in lowering blood pressure, oxidative stress, and inflammation (limited evidence).
  • Anti-inflammatory Support: P. cuspidatum extract (containing resveratrol) has been evaluated in clinical studies for anti-inflammatory effects (limited evidence).
  • Traditional Use: The root has been used in Traditional Chinese Medicine for a long time; extensive human studies for many uses are currently limited (traditionally).

Mechanism of Action and Active Components

Trans-resveratrol is an antioxidant and anti-inflammatory polyphenol that clears free radicals; its effects on endothelial function and cellular signaling pathways are being investigated.

Forms of Use (Tablet, Capsule, Powder)

The powder form can be used in tablet, capsule, powder mix/sachet, and (being water-soluble) liquid/syrup formulations.

Positive Plant List Check

Polygonum cuspidatum is included among the permitted (positive) plants under the Turkish Food Codex dietary supplement legislation. The permitted/used part: Root.

Usage Rate in Dietary Supplements

According to the Restricted Substances List for Dietary Supplements, a daily usage limit of 500mg/day applies to this component/extract.

Storage, Shelf Life, and Re-test

Store in a cool, dry, and protected from light environment. The recommended re-test period is generally 3 years; it may vary by manufacturer. The CoA document of the relevant batch shall be taken as the basis for the exact date.

Technical Documents and Supply — Asuka Kimya

You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for Polygonum Cuspidatum Extract 25:1.

References

  1. drugs.com

The usage information on this page is compiled from official herbal monographs and scientific literature (e.g., EMA/HMPC, NIH/NCCIH, Cochrane, EFSA). The product is a dietary supplement raw material and is not intended for the diagnosis or treatment of disease.