What is Secale Cereale Extract 4:1?
Secale Cereale Extract 4:1 is a standardized herbal extract (4:1) obtained from the Secale cereale plant. It is used as a raw material in dietary supplement production.
Product Properties
- Part used: Seed
- Standardization: 4:1
- Solubility: Water-soluble
| Analysis | Value |
|---|---|
| Moisture | ≤5.0 % |
| Total Heavy Metals | ≤10 ppm |
| E. Coli | Negative in 10 g |
| Salmonella | Negative in 25 g |
What is Secale Cereale Extract 4:1 Used For? What is its Purpose?
What is Secale Cereale Extract 4:1 used for? Rye (Rye Pollen), water and acetone-soluble pollen extract fractions (Cernitin T60 and GBX); containing amino acids and plant sterols, is a standardized herbal raw material used in dietary supplements to support symptoms of prostate (BPH) and urinary tract. Its standardized 4:1 content provides a consistent component source in formulations such as standardized pollen extracts (tablets/capsules) and powders.
Benefits and Main Uses of Secale Cereale Extract 4:1
- Benign Prostatic Hyperplasia (BPH) symptoms: Rye pollen extract (Cernilton) is one of the most studied phytotherapeutic agents for urinary symptoms associated with benign prostatic hyperplasia; it is a registered product in Western Europe, Japan, and Korea.
- Evidence status: A Cochrane review showed that Cernilton improved self-reported urinary symptoms compared to placebo in studies involving 444 men; however, the studies were short-term and small-scale (limited evidence).
- Chronic prostatitis support: Rye pollen is also used traditionally and clinically for complaints of chronic prostatitis and prostate pain.
- Anti-inflammatory effect: It is suggested that pollen extracts exhibit anti-inflammatory and smooth muscle relaxant effects in prostate tissue (mechanistic data).
Mechanism of Action and Active Components
It is suggested that rye pollen extract fractions exhibit anti-inflammatory effects in the prostate, relax urethral smooth muscle, and support bladder contraction.
Forms of Use (Tablet, Capsule, Powder)
The powder form can be used in tablet, capsule, powder mix/sachet, and (being water-soluble) liquid/syrup formulations.
Plant Positive List Check
The current Turkish Food Codex Plant List should be used to determine the status of this plant's use in dietary supplements. Part used: Seed.
Usage Rate in Dietary Supplements
According to the Restricted Substances List for Dietary Supplements, a daily usage limit of 500mg/day applies to this component/extract.
Storage, Shelf Life, and Re-test
Store in a cool, dry, and protected from light environment. The recommended re-test period is generally 3 years; it varies by manufacturer. The CoA document of the relevant batch should be used for the exact date.
Technical Documents and Supply — Asuka Kimya
You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for Secale Cereale Extract 4:1.
References
The usage information on this page is compiled from official herbal monographs and scientific literature (e.g., EMA/HMPC, NIH/NCCIH, Cochrane, EFSA). The product is a dietary supplement raw material; it does not claim to diagnose or treat diseases.

