What is St. John's Wort Extract 10:1?
St. John's Wort Extract 10:1 is a standardized herbal extract (10:1) obtained from the Hunan huakang plant. It is used as a raw material in dietary supplement production.
Product Properties
- Part used: Aerial Parts
- Standardization: 10:1
| Analysis | Value |
|---|---|
| Moisture | ≤5.0 % |
| Total Heavy Metals | ≤10 ppm |
| E.Coli | Negative in 10 g |
| Salmonella | Negative in 25 g |
What is St. John's Wort Extract 10:1 Used For? What is its Purpose?
What is St. John's Wort Extract 10:1 used for? St. John's Wort (Hypericum perforatum) is a standardized herbal raw material used in dietary supplements to support symptoms of mild-to-moderate mental depression (depression), due to its content of hypericin and hyperforin, and flavonoids. With its standardized 10:1 content, the standardized extract (hypericin/hyperforin) provides a consistent source of ingredients in formulations such as capsules, tablets, tinctures, teas, and oils (for external use).
Benefits and Main Uses of St. John's Wort Extract 10:1
- Mild-to-moderate depression: St. John's Wort has been defined as an effective option for mild-to-moderate depression; Cochrane reviews have reported beneficial effects compared to placebo and similar responses to standard antidepressants.
- Comparison with standard antidepressants: In patients with depression, it showed similar responses compared to standard SSRIs, but with a significantly lower rate of discontinuation due to withdrawal/side effects.
- Mood support: It is traditionally used to help improve mood.
- Interaction warning: It has serious interactions with serotonergic drugs, birth control pills, and many other medications; concomitant use requires medical supervision. (Important safety warning.)
Mechanism of Action and Active Components
Primarily, it increases synaptic transmission and creates an antidepressant effect by inhibiting the synaptic reuptake of serotonin, norepinephrine, and dopamine, mainly due to hyperforin.
Forms of Use (Tablet, Capsule, Powder)
The powder form can be used in tablet, capsule, powder mixture/sachet, and (since it is water-soluble) liquid/syrup formulations.
Positive Plant List Check
Hunan huakang is included among the plants permitted for use (positive list) under the Turkish Food Codex dietary supplement regulations. The permitted/used part: Aerial Parts.
Usage Rate in Dietary Supplements
According to the Restricted Substances List for Dietary Supplements, a daily usage limit of 3mg/day applies to this component/extract.
Storage, Shelf Life, and Re-test
Store in a cool, dry, and protected from light environment. The recommended re-test period is generally 3 years; it varies by manufacturer. The CoA document of the relevant batch shall be taken as the basis for the exact date.
Technical Documents and Supply — Asuka Kimya
You can contact Asuka Kimya for SDS, TDS, CoA, and supply conditions for St. John's Wort Extract 10:1.
References
The usage information on this page is compiled from official herbal monographs and scientific literature (e.g., EMA/HMPC, NIH/NCCIH, Cochrane, EFSA). The product is a dietary supplement raw material; it does not aim to diagnose or treat diseases.